The world has gone to hell... A nuclear war has left the Earth as a wasteland where the skies are red and ravaged by chemical mists. The United States of America along with the rest of the world has become "The Deathlands" where red-eyed mutants roam the lands and evil tyrants rules communities called "Viles". Ryan Cawdor is the one-eyed leader of a band of desert scavengers who have been living in "The Deathlands" for many years, as Ryan and his group scavenge what they can find and try to rebuild civilization along with the rest of the world. Ryan and his band returns to the vile "Front Royale", only to find "Front Royale" is ruled by his evil brother Harvey and stepmother Rachel who 20 years earlier murdered Ryan's father and wounded Ryan so they could rule the vile for themselves. With help of companions, Weapons expert JB Dix, Ryan's girlfriend Krysty Worth and teenage mutant Jak Laurent, Ryan sets out to avenge his past and put a end to Harvey and Rachel's reign of evil.